Psychopharmacology (Berlin) 2014;231:35693580. Accessed Oct. 28, 2021. Do tests to see pregnenolone, progesterone, testosterone, DHT, thyroid (TSH, total and free T4 and T3, rT3), estradiol, estrone-sulfate and cortisol (both blood and 24h saliva). Please note the date of last review or update on all articles. A mod answered and I answered the guy in a normal way, but they deleted my reply and blocked my account. 2015 Sep;16(3):177-98. doi: 10.1007/s11154-015-9319-y. If we cant discuss potential cures then that forum is completely worthless and I start to doubt their real intentions. I haven't had that sort of performance since I was 19 or 20 years old. Male pattern baldness develops when DHT binds to receptors in the scalp and causes the hair follicles to miniaturize. I had all the classic symptoms. Ejaculation and orgasm disorders. Ive seen this several times over there. Finasteride Depending on the likely cause of your dry orgasms and whether you need evaluation and treatment to help you get your female partner pregnant, you might need to see a urinary and reproductive specialist (urologist). Some people had to use anabolic steroids because herbs weren't strong enough. Unable to load your collection due to an error, Unable to load your delegates due to an error. I went from barely able to get an erection to having 4 very pleasurable orgasms on the third day. Next steps is likely getting a Hey there, Retrograde ejaculation can be especially challenging if you and your partner want to conceive a child. When did you first begin having dry orgasms? Note that prior to this protocol I tried injectable Test enanthate, Masteron, proviron and hcg which made my condition even worse. Retrograde ejaculation - Diagnosis and treatment - Mayo Clinic I cycled herbal androgen boosting supplements combined with intense workouts (I am a bodybuilder). two months back to life after being dead for six years. Certain medications used to treat retrograde ejaculation can increase your blood pressure and heart rate, which can be dangerous if you have high blood pressure or heart disease. Even my genitals began to grow normal size again. Your doctor might also do a physical exam that includes examining your penis, testicles and rectum. Get the latest in health news delivered to your inbox! Tamoxifen I did 20mg during the four weeks every day. And posted the article and some cliffs about his solution. 2016;93:9. I dont really understand why theyre like that. A review of the FAERS data on 5-alpha reductase inhibitors: implications for postfinasteride syndrome. This can be caused by damage to the prostate or semen-producing glands as a result of surgery or radiation treatment for cancer in the pelvic area. Very controversial topic in this forum. I'll never be without this stuff again. Archivio Istituzionale della Ricerca Unimi, NCI CPTC Antibody Characterization Program, Agis-Balboa R.C., Guidotti A., Pinna G. 5alpha-reductase type I expression is downregulated in the prefrontal cortex/Brodmann's area 9 (BA9) of depressed patients. | How To Diagnose And Reverse It. (Read up on desensitization of Leydig Cells but don't get nervous at this plan) Lol, now they banned me, just look at the reason: Dismissive of survey in first few posts; insistently advocated for dangerous and misleading article on PFS. Case report: a study of the clinical characteristics and genetic variants of post-finasteride syndrome patients. Is my condition likely temporary or chronic? Accessed Oct. 28, 2021. In order to achieve a pregnancy, you need to ejaculate enough semen to carry your sperm into your partner's vagina and into her uterus. Day 1 I felt no difference. Effect of 5-Reductase Inhibitors on Sexual Function: A Meta-Analysis and Systematic Review of Randomized Controlled Trials. Finasteride WebPost finasteride syndrome is real. Do they benefit from people who have pfs so their foundation can continue and ask for more donations? At first, I felt absolutely miserable when doing so, it is the worst Ive felt in my life and I was unable to do almost anything but after some weeks it became more tolerable as the receptors lost some of their sensitivity. Crazy, but true! BONUS! Before Preparing a list of questions before your appointment can help you make the most of your time together. Finasteride blocks the metabolism of testosterone. It is available as a generic. His article with all the studies hes referencing: Post Finasteride Syndrome can be manually corrected by interpreting blood work and implementing an appropriate lifestyle and/or pharmacological protocol. You can't get worse than living with no dick dude. I'll be interested to see if this has any effects on my weight loss endeavors. Sometimes, more-advanced assisted reproductive techniques are needed. Partin AW, et al., eds. rash. I did a cycle of hcg 250ui m/w/f for 6 months + a week and a half of clomid 25 everyday + DHEA (I know I'm a idiot) More or less cured me from no low libido and all that great stuff for over a year now and I'm off everything. more https://www.jasonemermd.com/cosmetic-dermatology/regenerative-medicine/hormonal Mod also deleted my second post where I said he indeed has affiliate links to herbs but doesnt even believe that will be enough for pfs patients, the real cure is proviron. Midodrine, a medicine that constricts blood vessels. Am I at risk of complications from this condition? I am not aware of the use of Human Growth Hormone in the treatment for Post Finasteride Syndrome. I feel deeply for all my balding brothers out there who are suffering from this poison. Chicago Man: Taking Propecia is the Biggest Regret Post-finasteride Syndrome Were on our own to beat this, just wait is the worst solution to pfs there is. Q. I have heard that finasteride, which I take for my prostate problem, can cause permanent impotence. I did a limited search and did not find other such claims. I dunno, I dont get it. The Damaging Side Effects of Finasteride - Ben's Natural Health Diagnosing and Reversing It", Is Post Finasteride Syndrome Real? Mesterolone (Proviron) is one of the best compounds that can be used for treating Post Finasteride Syndrome in my opinion. https://old.reddit.com/r/steroids/comments/m5m7o9/help_steroids_for_pssd/gr0uhqj/. 2018;120:143149. How much worse can it get then being a lifeless piece of flesh that hasnt been erect or had any kind of sensation in months and months? On a sidenote i've seen a few other people recover the same way. Finasteride oral tablet side effects: How to manage them I was one of the lucky guys who recovered from Test injections, https://old.reddit.com/r/steroids/comments/igyd61/offtopic_daily_chat_20200826/g2ym80n/. sharing sensitive information, make sure youre on a federal The supplement is making real changes in my body and mind, and it feels incredible. Eliminate Trigger Foods. Should I be concerned? Stop watching porn, stop masturbating, forget about sex, meditate, take cold showers, try breathing exercises, try extended water fasting. Epub 2016 Jul 27. I have the desire for sex and intimacy but my brain simply wont communicate with my penis when its time for intercourse. Post-Finasteride Syndrome: Current Views and Where do we Stand? Ive personally recovered from pfs but what worked for me may not work for you as each of our bodies react differently to this condition depending on individuals factors. The guy who made this thread and gave his opinion was banned too. They kept saying it was on the verge of having a major announcement 2 YEARS ago. Adverse effects of 5-reductase inhibitors: What do we know, don't know, and need to know? Adverse effects of common medications on male fertility. In some cases, sperm can be recovered from the bladder, processed in the laboratory and used to inseminate your partner (intrauterine insemination). Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Sign up to get tips for living a healthy lifestyle, with ways to fight inflammation and improve cognitive health, plus the latest advances in preventative medicine, diet and exercise, pain relief, blood pressure and cholesterol management, andmore. Last time I was on there they had started discussing some relationships between HCG and Thyroid? Proton-pump inhibitors: Should I still be taking this medication? What medications or herbal remedies do you take? Plentiful in opinions, short on facts. Just bombarding their bodies with strong androgens. AR: androgen receptor; CSF: cerebrospinal fluid; MRI: magnetic resonance imaging; SRD5A2: 5 alpha reductase type 2 gene. Post-finasteride syndrome: a surmountable challenge for clinicians. Post-finasteride syndrome - does it really exist? - PubMed Drugs to treat retrograde ejaculation are drugs primarily used to treat other conditions, including: Imipramine, an antidepressant. PDF | Finasteride was patented in 1984 and approved for medical use in 1992. I have been prescribed a 2.5% DHT gel that is applied to the shoulders and forehead once a day. It can prevent hair loss and decrease prostate enlargement, but not surprisingly, it can also suppress sexual function. No interest in sex at all. When you are on TRT, your DHT levels tend to go out of the normal range and finasteride is a mechanism for bringing it back into range. Do you have cloudy urine after an orgasm? For details, see text. Finally Cured From Post Finasteride Syndrome | Ray Peat Samplaski MK, et al. I was on TRT when I got PFS. Therefore, I cut the pills in half (2.5mg) and toss the other half. It can cause bladder and urination problems. Not orgasm strength and sperm levels have returned, just waiting on my brain to communicate with my penis when its time for sexual intercourse. Perhaps if I had tried it longer it would have helped more, Im not sure. Andracim Gel (small 2 eminem size, 1 on each size of rib cage, less is more with this stuff). ._9ZuQyDXhFth1qKJF4KNm8{padding:12px 12px 40px}._2iNJX36LR2tMHx_unzEkVM,._1JmnMJclrTwTPpAip5U_Hm{font-size:16px;font-weight:500;line-height:20px;color:var(--newCommunityTheme-bodyText);margin-bottom:40px;padding-top:4px;text-align:left;margin-right:28px}._2iNJX36LR2tMHx_unzEkVM{-ms-flex-align:center;align-items:center;display:-ms-flexbox;display:flex}._2iNJX36LR2tMHx_unzEkVM ._24r4TaTKqNLBGA3VgswFrN{margin-left:6px}._306gA2lxjCHX44ssikUp3O{margin-bottom:32px}._1Omf6afKRpv3RKNCWjIyJ4{font-size:18px;font-weight:500;line-height:22px;border-bottom:2px solid var(--newCommunityTheme-line);color:var(--newCommunityTheme-bodyText);margin-bottom:8px;padding-bottom:8px}._2Ss7VGMX-UPKt9NhFRtgTz{margin-bottom:24px}._3vWu4F9B4X4Yc-Gm86-FMP{border-bottom:1px solid var(--newCommunityTheme-line);margin-bottom:8px;padding-bottom:2px}._3vWu4F9B4X4Yc-Gm86-FMP:last-of-type{border-bottom-width:0}._2qAEe8HGjtHsuKsHqNCa9u{font-size:14px;font-weight:500;line-height:18px;color:var(--newCommunityTheme-bodyText);padding-bottom:8px;padding-top:8px}.c5RWd-O3CYE-XSLdTyjtI{padding:8px 0}._3whORKuQps-WQpSceAyHuF{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px}._1Qk-ka6_CJz1fU3OUfeznu{margin-bottom:8px}._3ds8Wk2l32hr3hLddQshhG{font-weight:500}._1h0r6vtgOzgWtu-GNBO6Yb,._3ds8Wk2l32hr3hLddQshhG{font-size:12px;line-height:16px;color:var(--newCommunityTheme-actionIcon)}._1h0r6vtgOzgWtu-GNBO6Yb{font-weight:400}.horIoLCod23xkzt7MmTpC{font-size:12px;font-weight:400;line-height:16px;color:#ea0027}._33Iw1wpNZ-uhC05tWsB9xi{margin-top:24px}._2M7LQbQxH40ingJ9h9RslL{font-size:12px;font-weight:400;line-height:16px;color:var(--newCommunityTheme-actionIcon);margin-bottom:8px} Ran [Tbol] 250mg for 2 months increased the dosages anywhere from 500mg to 1000mg. 2023 by The President and Fellows of Harvard College, Do not sell my personal information | Privacy Policy. My doctor put me on 5mg daily cialis (+up to 15mg as needed before sex) clomiphene 25mg/daily anastrozole 1mg/week Addyi shockwave therapy ($3000 for 6 sessions) though this is definitely unnecessary and experimental. Many men with retrograde ejaculation are able to get their partners pregnant once they seek treatment. I am 100% reversed Keep in mind if I miss a dose or stop my protocol Pfs comes back full force. 150mg/ day transdermal Testosterone gel applied to scrotum - 50mg/ day DHT gel applied to inner forearms and penis - 50mg oral pregnenolone/25mg DHEA daily, https://old.reddit.com/r/FinasterideSyndrome/comments/u1svwo/has_anyone_else_recovered_from_watery_semen_and/i4eg1it/?context=999. Over time, several studies have demonstrated that finasteride is a safe and well-tolerated drug, with rare and reversible side effects such as reduced sexual libido and ejaculatory volume, most commonly observed when prescribed in Metab. After numerous labs, I have determined that a dose of 2-3 mg is optimal for keeping my DHT within the normal range. While most men can get their female partners pregnant with infertility treatment, it can be costly and require stressful medical procedures for both you and your partner. Therefore, understand that I can't promise this will work for youbut for me? Serious Side Effects: Post Finasteride Syndrome This site complies with the HONcode standard for trustworthy health information: verify here. FINASTERIDE That's one of the mildest forms of PFS you can experience. You're right. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Book: Mayo Clinic Guide to Fertility and Conception. If youre experiencing a medical issue, please contact a healthcare professional or dial 911 immediately. Next to no sensitivity in my genitals. To be honest, I think for the most part these recoveries werent PFS but rather hormonal imbalances. Federal government websites often end in .gov or .mil. Management of the dry ejaculate: A systematic review of aspermia and retrograde ejaculation. Urology. .FIYolDqalszTnjjNfThfT{max-width:256px;white-space:normal;text-align:center} Accessed Sept. 15, 2016. .ehsOqYO6dxn_Pf9Dzwu37{margin-top:0;overflow:visible}._2pFdCpgBihIaYh9DSMWBIu{height:24px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu{border-radius:2px}._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:focus,._2pFdCpgBihIaYh9DSMWBIu.uMPgOFYlCc5uvpa2Lbteu:hover{background-color:var(--newRedditTheme-navIconFaded10);outline:none}._38GxRFSqSC-Z2VLi5Xzkjy{color:var(--newCommunityTheme-actionIcon)}._2DO72U0b_6CUw3msKGrnnT{border-top:none;color:var(--newCommunityTheme-metaText);cursor:pointer;padding:8px 16px 8px 8px;text-transform:none}._2DO72U0b_6CUw3msKGrnnT:hover{background-color:#0079d3;border:none;color:var(--newCommunityTheme-body);fill:var(--newCommunityTheme-body)} 2015;104:107. Make a donation. Incredible! /*# sourceMappingURL=https://www.redditstatic.com/desktop2x/chunkCSS/IdCard.ea0ac1df4e6491a16d39_.css.map*/._2JU2WQDzn5pAlpxqChbxr7{height:16px;margin-right:8px;width:16px}._3E45je-29yDjfFqFcLCXyH{margin-top:16px}._13YtS_rCnVZG1ns2xaCalg{font-family:Noto Sans,Arial,sans-serif;font-size:14px;font-weight:400;line-height:18px;display:-ms-flexbox;display:flex}._1m5fPZN4q3vKVg9SgU43u2{margin-top:12px}._17A-IdW3j1_fI_pN-8tMV-{display:inline-block;margin-bottom:8px;margin-right:5px}._5MIPBF8A9vXwwXFumpGqY{border-radius:20px;font-size:12px;font-weight:500;letter-spacing:0;line-height:16px;padding:3px 10px;text-transform:none}._5MIPBF8A9vXwwXFumpGqY:focus{outline:unset} Ive seen many others who give their opinion but are banned as a result. This is not proof that finasteride is to blame, since a variety of medical conditions and other prescription drugs could explain the sexual symptoms. The dosage needs to be low and steady, do not increase or add a day thinking more is better. Common finasteride side effects include loss of libido, breast enlargement, erectile dysfunction (ED), and lower ejaculatory volume. Treatment for Post Finasteride Syndrome There is no known treatment of PFS. Mayo Clinic is a not-for-profit organization. Bookshelf Finasteride blocks the metabolism of testosterone. Accessibility No energy. Your doctor will ask you to empty your bladder, masturbate to climax and then provide a urine sample for laboratory analysis. WebIn addition to the sexual, mental and physical side effects, PK suffers from miscellaneous issues connected with PFS. Have you been on hackstasis? TRT so thats why I went down this rabbit hole. Mods are always talking about the survey too, I said a survey wont cure us and we could be be waiting for 10 years if we dont do anything. I tried just about everything over 11 years. Yeah, yeah. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. 2016;101:46694680. Gut Inflammation Induced by Finasteride Withdrawal: Therapeutic Effect of Allopregnanolone in Adult Male Rats. Post-finasteride syndrome (PFS) is defined as a syndrome with symptoms that can include erectile dysfunction (ED), decreased libido, fatigue, penile and scrotal atrophy and numbness, gynecomastia, muscle atrophy, anxiety, blunted affect, and emotional sensitivity in patients who have taken 5-reductase inhibitors such as finasteride or 5alpha-reductase; Androgenetic alopecia; Depression; Finasteride; Neuroactive steroids; Sexual dysfunction. The site is secure. A. Finasteride (sold as Proscar and generic brands) is prescribed for symptoms of an enlarged prostate; it's also used at a lower strength (under the name Propecia) for male pattern baldness. I'm not a gym rat, I just make sure to walk 3-5 miles a day and do my best to watch what I eat (that's always been the case.) Im glad I did. Answer: Hormonal optimization while on finesteride there are many options including peptides, and HCG as well as clomid/arimidex. To give you a bit of background, I'm a 34 year old male whose sexual function was utterly destroyed by finasteride/Propecia. -, Alkahtane A.A., Albasher G., Al-Sultan N.K., Alqahtani W.S., Alarifi S., Almeer R.S., Alghamdi J., Ali D., Alahmari A., Alkahtani S. Long-term treatment with finasteride induces apoptosis and pathological changes in female mice. 2022 Oct 26;12(11):1567. doi: 10.3390/biom12111567. I just decided to get back on gear after a year off + dutasteride during that time. I only said everyone should read it, especially in light of the big new proviron recovery on the forum there. But on day 3, I felt like my old self. https://camas.github.io/reddit-search/#{%22author%22:%22mrgoodcat1990%22,%22resultSize%22:100,%22query%22:%22pssd%20numbness%22}, ._3K2ydhts9_ES4s9UpcXqBi{display:block;padding:0 16px;width:100%} Examples include bladder neck surgery and transurethral resection of the prostate. A community dedicated to people suffering long term effects after taking 5-ar inhibitors such as Propecia/Finasteride, or for people who wish to know more about the constellation of symptoms commonly known as Post Finasteride Syndrome. https://old.reddit.com/r/FinasterideSyndrome/comments/psjeuu/could_trying_finasteride_for_1_month_be_harmfull/he38hlf/. After a few days I starting liking women again and became sexually from frustrated. Disclaimer. I feel like I have my life back.