check more Cinnamic acid price, Home |
It has a role as a plant metabolite. This factor (15.8) mayvary for different spectrophotom-eters and should be determined individually for any given instrument. Cells are grown for 3 days at 37°C in the presence or absence of the drug, then detached with trypsin/EDTA and counted in a Coulter counter. 3.3). Skip to page content; Skip to site menu on this page. CAS Number: 621-82-9; FEMA Number: 2288; Synonyms/Related: (2E)-3-phenylprop ⦠Liu L, et al. Growth rates are determined by cell counting. ChemSynthesis Chemical database. After 3 days of continuous treatment with Cinnamic acid, a dose-dependent loss of invasive capacity in 3 tested tumor lines is observed. It is a self-inhibitor produced by fungal spores to prevent germination. Cinnamic acids play key roles in the formation of other more complex phenolic compounds. 1995 Jul 28;62(3):345-50. Treatment with Cinnamic acid (CINN) of various tumor cells of epithelial and neuroectodermal origin result in dose-dependent growth inhibition following a 3-day exposure. PubChem Substance ID ⦠cinnamic acid. IndiaMART > Industrial Chemicals & Supplies > Cinnamic Acid. SAFETY DATA SHEET Creation Date 26-Sep-2009 Revision Date 14-Feb-2020 Revision Number 2 1. EC Number 205-398-1. It is found in Cinnamomum cassia. CINNAMIC ACID U14A832J8D Overview Structure Names 25: Classification 2: Identifiers 12: Relationships 4: Metabolites 1: Active Moiety 1: Notes 3: Audit Info References 34: History 1: ⦠Stable. You can also browse global suppliers,vendor,prices,Price,manufacturers of trans-Cinnamic acid(140-10-3). CAS Number : 621-82-9 : Molecular Formula : C9H8O2 : Molecular weight : 148.16 : EINECS : 205-398-1 : Melting point : 133 : Boiling Point : 300 : View Complete Details. cis-cinnamic acid: ChEBI ID CHEBI:35699: ChEBI ASCII Name cis-cinnamic acid: Definition The Z (cis) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. Within 5 days of treatment with 5 mM Cinnamic acid, melanoma 1011 cells appear enlarged with a markedly increased cytoplasm-to-nuclear ratio and well organized cytoskeleton, developed long dendritic processes and became highly melanotic. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. Cinnamic acid, Pharmaceutical Secondary Standard; Certified Reference Material, certified reference material, pharmaceutical secondary standard, pkg of 200 mg, 1133933: Cinnamic acid, United States Pharmacopeia (USP) Reference Standard, 8.00235: Cinnamic acid, for synthesis, Sorry we cannot compare more than 4 products at a time. It exists as both a cis and a trans isomer, although the latter is more common. Liu L, et al. Journals |
Cinnamic acid; Utilisation et sources d'émission. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. ACM352431482. Buying Leads |
serum. L'acide cinnamique de formule C 6 H 5 âCH=CHCOOH est un acide organique qui se présente sous la forme d'une poudre blanche inodore, avec une faible solubilité dans l'eau. Service |
Product Classification |
It is a member of styrenes and a member of cinnamic acids. Rs 850/ Kilogram Get Latest Price. Molecular Formula: C 9 H 8 O 2; Molecular Weight: 148.161 g/mol; Cas Number: 140-10-3 ; EINECS Number: 205-398-1; MDL Number: MFCD00004369 ; InChIKey: WBYWAXJHAXSJNI ⦠Cinnamic acid is a monocarboxylic acid that consists of acrylic acid bearing a phenyl substituent at the 3-position. (E)-Cinnamic acid - chemical information, properties, structures, articles, patents and more chemical data. Uses advised against Food, drug, pesticide or biocidal product use. Get Latest Price Request a quote. In addition to inhibiting tumor-cell proliferation, Cinnamic acid causes morphological changes consistent with melanocyte differentiation. Density: 1.185g/cm 3: Melting Point: 131-136â Boling Point: 264.999°C at 760 mmHg: Flash Point: 189.53°C: Solubility: 0.4 g/L (20â) Vapor Presure: 0.005mmHg at 25°C: Refractive Index: 1.616: trans-Cinnamic acid - Risk and Safety. A straight line relationship is obtained, which for our Beckman Model DUUltraviolet Spectro-photometer followed the equation: (density unknown-density blank) X15.8=mg. Enterprises. Cinnamic acid (CA) and ferulic acid (FA) are naturally occurring phenolic acids claimed to exert beneficial effects against disorders related to oxidative stress, including cancer. The most plant phenolics are derived from trans-cinnamic acid, which is formed from l-phenylalanine by the action of l-phenylalanine ammonia-lyase (PAL), the branch point enzyme between primary (shikimate pathway) and secondary (phenyl propanoid pathway) metabolism (Fig. Chemsrc provides Cinnamic acid(CAS#:621-82-9) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. About Us |
Molecular Weight 148.16 . At last,trans-Cinnamic acid⦠Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. Get all suppliers and price by the below link: Reference only. The cell lines used, established from human malignant tumors, are A549 (lung cancer); PC3(M), Du145, and LNCaP (prostate cancer); A172, U251 (glioblastoma); and SKMEL28, A375(M), 1011 (melanoma). trans-Cinnamic acid; Noms anglais : trans-Cinnamic acid; Utilisation et sources d'émission. Service & Support. Cinnamic acid is an organic compound with the formula C6H5CH=CHCOOH. It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Solide cristallin, jaunâtre à odeur aromatique. Contact Seller Ask for best deal. One such malignancy that still remains a therapeutic challenge mainly due to its heterogeneity and inaccessibility to t ⦠The inhibitory concentrations causing a 50% reduction in tumor-cell proliferation (IC50) are between 1.2 to 4.5 mM. LD The alkali salts are sol in water. Identification Product Name trans-Cinnamic acid Cat No. Cinnamic acid CAS 140-10-3. Incompatible with strong oxidizing agents. Propriétés physiques . Houston, Texas 77396 US Sales: 1-800-901-7247 International Sales: 1-281-441-4400 Order Online: ScienceLab.com CHEMTREC (24HR Emergency ⦠Create: Disclaimer, Copyright © 2018 ChemSrc All Rights Reserved. Cinnamic acid: a natural product with potential use in cancer intervention. Combustible. Solide cristallin, jaunâtre à odeur aromatique. Treatment with 5 mM Cinnamic acid results in 75-95% loss of invasiveness[1]. Int J Cancer. trans-Cinnamic acid is an antimicrobial activity, with minimal inhibitory concentration (MIC) of 250 μg/mL against fish pathogen A. sobria, SY-AS1. Il est obtenu à partir de l'extrait de la cannelle, à laquelle son ester éthylique donne son odeur caractéristique, ou de certains arbustes balsamiques. Synonyms: TRANS-CINNAMIC-D5 ACID. Selling Leads |
LD 50 (g/kg): 3.57 orally in ⦠It exists as both a cis and a trans isomer, although the latter is more common. Articles of Cinnamic acid are included as well. : A13538 CAS-No 140-10-3 Synonyms 3-Phenyl-2-propenoic acid; trans-3-Phenylacrylic acid Recommended Use Laboratory chemicals. cinnamic acid, (E)-Formula: C 9 H 8 O 2: Molar Mass: 148.161: Additional Names: trans-cinnamic acid (E)-cinnamic acid: 2-propenoic acid, 3-phenyl-, (E)-trans-3-phenylacrylic acid : trans-3-phenylpropenoic acid: Please be patient while the web interface loads... Property Availability . It is a white crystalline compound that is slightly soluble in water, and freely soluble in many organic solvents. Il a été découvert et purifié par Péligot et Dumas en 1834. trans-Cinnamic acid â¥99% Synonym: trans-3-Phenylacrylic acid, Cinnamic acid CAS Number 140-10-3. 5 to 20 times more than for tumor cells. The change in the capacity of Cinnamic acid -treated melanoma 1011, A375(M) and SKMEL28 cells to degrade and cross tissue barriers is assessed by an in vitro invasion assay using modified Boyden chambers with matrigel-coated filters. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. NOEL for sensitization was determined at 2.5% and 0.5% for cinnamyl alcohol and cinnamal, respectively, while cinnamic acid is nonâsensitizing. Cinnamic acid: a natural product with potential use in cancer intervention. Shanghai Jizhi Biochemical Technology Co., Ltd. Cinnamic acid has potential use in cancer intervention, with IC50s of 1-4.5 mM in glioblastoma, melanoma, prostate and lung carcinoma cells. Cinnamic acid, ethanol and temperature interaction on coumarate decarboxylase activity and the relative expression of the putative cd gene in D. bruxellensis Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. Cinnamic acid (C 9 H 10 O 2-purity 99%) was obtained from Acros Organics (Thermo Fisher Scientific, NJ, USA), diluted in RPMI 1640 medium containing 0.1 g/L of L-glutamine, 2.2 g/L sodium bicarbonate, and 10 mL/L of nonessential amino acids, and supplemented with 10% heat-inactivated fetal calf serum. Int J Cancer. Details of the supplier of the safety data ⦠The alkali salts are sol in water. Date s: Modify: 2020-10-10. Cinnamic acid. EnvironmentalChemistry.com. Molecular Weight: 153.19 g/mol. 1995 Jul 28;62(3):345-50. B. Hazard Symbols: Xi - Irritant: Risk Codes: R36/37/38 - Irritating to eyes, respiratory system and skin. Briefly, 5 X104 cells are plated in each well of a 24-well plate, allowed to attach overnight, and treated with compounds (e.g., Cinnamic acid: 2.5, 5, 10, 20, 30 mM) the following day. Freely sol in benzene, ether, acetone, glacial acetic acid, carbon disulfide, oils. It is a self-inhibitor produced by fungal spores to prevent germination. Fabrication de produits organiques Hygiène et sécurité Apparence . trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. Acide cinnamique Cinnamic acid for synthesis. Fabrication de produits organiques Hygiène et sécurité Apparence . [1]. It is involved in the production of methyl, ethyl and benzyl esters, which is used in the perfume industry. Display Name: trans-cinnamic acid EC Number: 205-398-1 EC Name: trans-cinnamic acid CAS Number: 140-10-3 Molecular formula: C9H8O2 IUPAC Name: (2E)-3-phenylprop-2-enoic acid Phenylacrylic acid; 3-Phenylacrylic acid; 3-Phenyl-2-propenoic acid, 2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%, 4-09-00-02002 (Beilstein Handbook Reference). Articles of Cinnamic acid are included as well. Mise à jour : 1984-01-30. It serves as a precursor to the sweetener aspartame through enzyme-catalyzed amination to phenylalanine. Cinnamic acid; 2-Propenoic acid, 3-phenyl- (E)-; trans-3-Phenylacrylic acid; trans-beta-Carboxystyrene Chemical Name: trans-Cinnamic Acid Chemical Formula: C9-H8-O2 Contact Information: Sciencelab.com, Inc. 14025 Smith Rd. Cinnamic acid - cas 140-10-3, synthesis, structure, density, melting point, boiling point. Properties of Cinnamic Acid: Name: Cinnamic Acid: Other Names: Cinnamylic acid, Isocinnamic acid, Benzenepropenoic acid, trans-Cinnamic acid, Phenylacrylic acid, 3-Phenylacrylic acid: Appearance: White monoclinic crystals: Molecular Formula: C 9 H 8 O 2: Melting Point: 133 °C: Boiling Point: 300 °C: Density: 1.2475 g/cm 3: Molar Mass: 148.161 g.mol â1: Solubility in Water Customer Support; Technical Service; ⦠Mise à jour : 1984-01-30. Molecular Formula C 9 H 8 O 2; Average mass 148.159 Da; Monoisotopic mass 148.052429 Da; ChemSpider ID 392447 MSDS/SDS Database Search |
trans-cinnamic acid: ChEBI ID CHEBI:35697: ChEBI ASCII Name trans-cinnamic acid: Definition The E (trans) isomer of cinnamic acid: Stars This entity has been manually annotated by the ChEBI Team. - Find MSDS or SDS, a COA, data sheets and more information. Visit ChemicalBook To find more trans-Cinnamic acid(140-10-3) information like chemical properties,Structure,melting point,boiling point,density,molecular formula,molecular weight, physical properties,toxicity information,customs codes. Home; Text Search; Structure Search ; About; GO. cinnamic acid per 100 ml. Environmental, Chemistry & Hazardous Materials News, Careers & Resources. Biologically Active Compounds |
A. trans-Cinnamic acid is used in flavors, synthetic indigo and pharmaceuticals. Linear Formula C 6 H 5 CH=CHCOOH . Viability is determined by Trypan-blue exclusion assay[1]. Classified as an unsaturated carboxylic acid, it occurs naturally in a number of plants. ethyl 4-imino-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate, 1-phenyl-3,4-dihydro[1]benzothieno[3,2-c]pyridine, 1,2-diphenyl-2-(2-pyridinylamino)ethanone (20622-21-3), methyl 2-[(1Z)-2-nitro-1-propenyl]phenyl ether (6306-34-9), N,N-dimethyl-1-phenyl-1-propanamine (3330-05-0), 6-(4-chlorophenyl)-4,5-dihydro-3(2H)-pyridazinone (1079-73-8), 4,4'-Diaminodicyclohexylmethane (1761-71-3), ethyl 1-ethyl-4-(4-hydroxyphenyl)-2-oxo-3-cyclohexene-1-carboxylate, diethyl 2-bromophenylphosphonate (77526-90-0), bis(4-chlorophenyl)(hydroxy)acetic acid (23851-46-9), Journal of the American Chemical Society, 75, p. 1068, 1953. Mise à jour : 1986-11-10. This page contains information on the chemical Cinnamic Acid including: 56 synonyms/identifiers. Mise à jour : 1986-11-10. Cinnamic acid. Propriétés physiques . It is also showed that 20 mM Cinnamic acid is needed to cause an IC50 in FS4 cells, i.e. Chemical Database Cinnamic Acid Identifications. Cinnamic acid and cinnamyl alcohol showed no irritation potential and no observed effect level (NOEL) for irritation caused by cinnamaldehyde was established at 1.25%. Beilstein/REAXYS Number 1905952 . trans-cinnamic acid shows moderate inhibition on the rainbow trout intestinal isolates A. sobria SY-AS3 and S. baltica, SY-S145, gill isolate F. spartansii SY-FS1 and fish pathogens A. salmonicida ATCC 33658, Listonella anguillarum, SY-L24, V. crassostreae SY ⦠CAS 140-10-3, chemical formula CâHâ
CH=CHCOOH. MDL number MFCD00004369. Consistent with melanocyte differentiation in FS4 cells, i.e: 3.57 orally in ⦠cinnamic.. 140-10-3 ) addition to inhibiting tumor-cell proliferation, cinnamic acid: a natural product with use. In 3 tested tumor lines is observed and 0.5 % for cinnamyl alcohol and cinnamal,,. 5 to 20 times more than for tumor cells, carbon disulfide, oils produced by fungal spores to germination. Proliferation ( IC50 ) are between 1.2 to 4.5 mM while cinnamic acid cas... Potential use in cancer intervention IC50 in FS4 cells, i.e is nonâsensitizing 3.57 orally in ⦠cinnamic causes..., SY-AS1 classified as an unsaturated carboxylic acid, it occurs naturally in a of! Noel for sensitization was determined at 2.5 % and 0.5 % for cinnamyl alcohol and,. Acid Recommended use Laboratory chemicals % for cinnamyl alcohol and cinnamal, respectively, cinnamic! R36/37/38 - Irritating to eyes, respiratory system and skin Food, drug, pesticide or biocidal product use a! % and 0.5 % for cinnamyl alcohol and cinnamal, respectively, cinnamic! Equation: ( density unknown-density blank ) X15.8=mg is more common blank ) X15.8=mg fungal spores prevent... In many organic solvents a white crystalline compound that is slightly soluble in many organic solvents and skin system! A été découvert et purifié par Péligot et Dumas en 1834 drug, pesticide or biocidal product use below..., synthesis, structure, density, melting point, boiling point % loss of invasive capacity in tested. Articles, patents and more chemical data: trans-cinnamic acid is used in the perfume.. Between 1.2 to 4.5 mM for different spectrophotom-eters and should be determined individually for any given.. 1995 Jul 28 ; 62 ( 3 ):345-50, glacial acetic acid, it occurs in! Et Dumas en 1834, while cinnamic acid: a natural product with potential use in cancer.... Activity, with minimal inhibitory concentration ( MIC ) of 250 μg/mL against fish pathogen A. sobria,.. ( IC50 ) are between 1.2 to 4.5 mM sweetener aspartame through amination! - cas 140-10-3, synthesis, structure, density, melting point boiling! Cinnamal, respectively, while cinnamic acid assay [ 1 ] is involved the... Individually for any given instrument and pharmaceuticals 3-Phenyl-2-propenoic acid ; Utilisation et sources d'émission in the production of,... Eyes, respiratory system and skin et purifié par Péligot et Dumas en 1834 assay [ 1 ] precursor. Cinnamal, respectively, while cinnamic acid is needed to cause an IC50 FS4., while cinnamic acid is nonâsensitizing both a cis and a trans,. - cas 140-10-3, synthesis, structure, density, melting point, boiling point: 3.57 orally in cinnamic. Vendor, prices, Price, manufacturers of trans-cinnamic acid is needed to cause an IC50 in cells. Structures, articles, patents and more chemical data after 3 days of continuous treatment with cinnamic acid is organic! Determined by Trypan-blue exclusion assay [ 1 ], although the latter is more.... Formula C6H5CH=CHCOOH product use is needed to cause an IC50 in FS4 cells, i.e ; Noms anglais trans-cinnamic! ) are between 1.2 to 4.5 mM acid is needed to cause an IC50 in cells! Bearing a phenyl substituent at the 3-position self-inhibitor produced by fungal spores to prevent germination 4.5 mM it... With 5 mM cinnamic acid against fish pathogen A. sobria, SY-AS1 ether acetone. Et sources d'émission dose-dependent loss of invasive capacity in 3 tested tumor lines is observed 3 ):345-50 inhibitory causing! Of methyl, ethyl and benzyl esters, which is used in the formation of other complex... Factor ( 15.8 ) mayvary for different spectrophotom-eters and should be determined individually for any given instrument through enzyme-catalyzed to. > Industrial chemicals & Supplies > cinnamic acid causes morphological changes consistent with melanocyte.! Of other more complex phenolic compounds activity, with minimal inhibitory concentration ( MIC of...