We comply with the HONcode standard for trustworthy health information. 2 0 obj % Any long-term side effects/dangers from iron infusions? : r/Anemic - Reddit Terminal half-life ranges from 7 to 12 hours. Talk to your pharmacist for more details. Serious side effects should be reported to a physician and/or PharmD for medical advice. Cholesterolmedication may reduce the risk of a stroke but it can decrease the quality of life for some people but causingweight gain, dizziness, nausea, and musclepain. The oral form of the drug, called sucroferric oxyhydroxide and used . If you need financial support to pay for Injectafer, or if you need help understanding your insurance coverage, help is available. Learn how to store and discard medical supplies safely. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. If you have questions about using Injectafer for anemia during pregnancy, talk with your doctor. Upset stomach or throwing up. dizziness. Your doctor may also recommend that you take iron supplements by mouth (if you havent tried these supplements in the past). Symptoms of a serious allergic reaction may include: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. As described just above in the Allergic reaction section, some people may have an allergic reaction after getting a dose of Injectafer. Most people do not know how long theirside effectswill last until they go through them. Side Effects of Venofer (Iron Sucrose Injection), Warnings, Uses - RxList Common side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting; diarrhea; These pregnancy-related problems include preterm delivery and low birth weight of your infant. For people with certain medical implants, such as pacemakers, an MRI may pose an . Other drugs may interact with iron sucrose, including prescription and over-the-counter medicines, vitamins, and herbal products. Keep out of reach of children. Injectafer comes as a liquid thats given by either intravenous (IV) infusion or slow IV injection. One class of immune checkpoint inhibitors targets the protein PD-1, which acts as a brake to keep the immune system in check. Treatment with Venofer injections can make it harder for your body to absorb iron medications you take by mouth. Then the study was split into the following two groups, which are discussed below. Properly discard this product when it is expired or no longer needed. Back pain. Call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. Tell your doctor if you are pregnant or plan to become pregnant. But for other people, their anemia may come back after Injectafer treatment. What to Know About Iron Infusions for Anemia Treatment - GoodRx This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. (And Injectafer is used to treat IDA.) They can recommend if this is safe for you to do. These effects typically last between 7 and 11 hours. Have blood work checked as you have been told by the doctor. Last updated August 20, 2020. Symptoms of a severe allergic reaction can include: Because of the risk of allergic reaction with Injectafer, your healthcare professional will monitor you for at least 30 minutes after you get each dose of the drug. In stock alternatives of Venofer (based on Iron Sucrose ) Orofer S 200 Injection 1 Injection in 1 Packet 540 569 5% off. <> IQVIA [NSP Audit from MAT November 2013 to November 2018]. Venofer 100 mg iron/5 mL intravenous solution, Venofer 50 mg iron/2.5 mL intravenous solution, Venofer 200 mg iron/10 mL intravenous solution, Select a condition to view a list of medication options. Drug interactions may change how your medications work or increase your risk for serious side effects. . Hes an expert in genetic testing, genetic analysis, andprecision medicine. There are currently no generic forms of either drug. Follow all instructions closely. But if they become more severe or dont go away, talk with your doctor or pharmacist. Your doctor will go over your Call your doctor for medical advice about side effects. HRT, like other medications, does have some side effects and these are thought to be quite common. Its not known for sure how often this condition occurred during clinical trials, or if it occurred at all during the trials. You will need to talk about the benefits and risks to you and the baby. Patients should induce vomiting or evacuate the stomach by lavage during Venofer overdoasge. If you think there has been an overdose, call your poison control center or get medical care right away. Daiichi Sankyo, Inc., the manufacturer of Injectafer, offers a program called injectconnect, which may help lower the cost of the drug. Their medical staff can help you set up another time to receive your Injectafer dose. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Consult the product instructions and your pharmacist for storage details. Its FDA-approved to treat iron deficiency anemia (IDA) in adults. intense abdominal pain. Venofer pregnancy and breastfeeding warnings. Weight changes may be due to symptoms of anemia improving. If you have any questions about Venofer, please talk with your doctor, nurse, pharmacist, or other health care provider. Allergic reactions typically occur the first time your body is exposed to a drug. Excessive amounts of Venofer may lead to a condition called iron overload, which may be harmful. Orofer S 50 Injection 1 Injection in 1 Packet 147. But its not known whether this poses any risk to a child whos breastfed. wAd**CgI%"nn{Oa[q{r5 They can give you tips on how to deal with any side effects that may be bothersome. Venofer is used to treat iron deficiency anemia in people with kidney disease. He is an Affiliate Specialist of the American College of Medical Genetics and Genomics(ACMG), an Associate of the American College of Preventive Medicine(ACPM), and a member of the National Society of Genetic Counselors(NSGC). It is very important that your doctor check you closely while you are receiving this medicine. Common Venofer side effects may include: fever, cold or flu symptoms ( sore throat, cough, stuffy nose, sneezing); high or low blood pressure; headache, dizziness; nausea, vomiting, diarrhea; muscle or joint pain, back pain; pain or swelling in an arm or leg; itching; or bruising or irritation where the medicine was injected. The actual price youll pay depends on your insurance plan and any copays, your location, and the pharmacy you use. Not all possible drug interactions are listed here. Allergic reaction As with most drugs, some people can have an allergic reaction after taking Injectafer. Copyright 1996-2023 Cerner Multum, Inc. Its given by either intravenous (IV) infusion or slow IV injection. It belongs to a class of medications known as iron replacement products. Injectafer and Feraheme can cause very similar side effects, but some different ones as well. One of the most commonly used tests to monitor IDA is the hemoglobin test. I hope you found answers and are feeling better now. And if you dont have an allergic reaction to your first dose of a drug, its typically safe to assume you wont have an allergic reaction to doses that follow. For people weighing less than 50 kg, administer Injectafer in two doses of 15 mg/kg of body weight, at least 7 days apart. Do not share your drugs with others and do not take anyone else's drugs. Depending on your anemia symptoms, your weight changes may be different than those described here. Venofer: Uses, Taking, Side Effects, Warnings - Medicine.com endobj How long it takes for the bodyto break down the meds matters and some peoples bodies simply take longer than others. A boxed warning is the most serious warning the Food and Drug Administration (FDA) can issue about a drug. In clinical trials,. Examples of thisinclude: Not allside effectslast forever. Usually, when drugs may cause an immune system reaction like this, its a concern with your first dose of the drug. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Vomiting. If youre sexually active and you or your partner can become pregnant, talk with your doctor about your birth control needs while youre taking Injectafer. So the goal of IDA treatment with Injectafer is to bring your hemoglobin level back to a value thats within normal range. Iron-refractory iron deficiency anemia (IRIDA) is a genetic form of anemia. Some may be a better fit for you than others. Others last much longer (even a lifetime), which can be quite traumatizing to people. In order for your body to make RBCs, your bone marrow needs a hormone called erythropoietin (EPO). Diarrhea. And this over-activation is what may lead to an allergic reaction or a delayed allergic reaction. Can diet help improve depression symptoms? For more information about taking Injectafer during pregnancy, see the section Injectafer and pregnancy above. Side effectswill last a very long time if the cause of them is not resolved. endobj Potential side effects that are usually mild may include, but are not limited to: Headache Nausea Dry Mouth Stomachache Dizziness Diarrhea Constipation These side effects may not impact life too much and may only be temporary. 5 0 obj In this group, after 35 days of treatment: Effectiveness of Injectafer compared with a different IV iron product. If the underlying cause of your anemia isnt addressed, theres a chance your anemia could come back after Injectafer treatment. These people may lose weight as their anemia improves because theyre more active. These drugs have been compared in a clinical trial of adults with both IDA and CKD who didnt need dialysis. This is why family members often have the same issues with drugs as others in theirfamily. What should I know regarding pregnancy, nursing and administering Venofer Vial to children or the elderly. The body cannot metabolize such a high dose fast enough, so it ends up affecting a part of the body it wasnt intended to, such as the stomach. weakness. Weight influences how fast medication breaks down in the body, so it also affects how longside effectswill last. Generics tend to cost less than brand-name drugs. This gives a total cumulative dose of 1,500 mg of Injectafer. Can poor sleep impact your weight loss goals? Its responsible for carrying oxygen throughout your body. This information should not be used to decide whether or not to take Venofer or any other medicine. If you have questions about drinking alcohol while youre taking Injectafer, talk with your doctor. Venofer is indicated to treat iron deficiency anemia (IDA) in adult and pediatric patients (2 years and older) with chronic kidney disease (CKD). In the studies, peoples hemoglobin level was measured to check for improvement in their anemia. Generic name: iron sucrose (injection) [EYE-urn-SOO-krose] Yes, in some cases it may. Call your doctor right away if you have chest pain, cough or the need to cough, dizziness, passing out, shortness of breath, sweating, or throat tightness. And this can affect how well those parts of your body are able to work. They can recommend appropriate treatment options. In Canada - Call your doctor for medical advice about side effects. 4 0 obj Potential injection site discoloration has happened. Injectafer contains the active drug ferric carboxymaltose. Examples of other drugs that may be used to treat IDA include: Your doctor will recommend the drug thats right for you depending on the severity of your anemia and any other medical conditions you may have. But even if youre not at risk for the condition, your doctor may still monitor your phosphorus levels. Severeside effectsmay end up causing a lot of disruption in a persons life. You will be watched closely by your doctor for 30 minutes after each dose. Sharing this information can help you avoid potential interactions. It is usually given slowly over 2 to 5 minutes or as directed by your doctor. But call 911 if your symptoms feel life threatening or if you think youre having a medical emergency. For some people, after receiving one treatment course (two doses) of Injectafer, their IDA is resolved. Does Daxxify Work Better Than Botox? I Tried The New Neurotoxin. You may report side effects to FDA at 1-800-FDA-1088. For example, if someone takes 100 mg of a drug, only half of it will be in the bloodstream in a couple ofhours. Only 10 mg may be excreted by the body the next time it goes through the liver, and possibly only 5 mg the nextpass. In one study, treatment with Injectafer was compared with that of iron thats taken by mouth. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. We cancelled my 5th because of the reaction. With IDA, you have low hemoglobin levels. If you are allergic to Venofer; any part of this medicine; or any other drugs, foods, or substances. If you have questions about the safety of breastfeeding while youre taking Injectafer, talk with your doctor. Reactions around the injection/infusion site, such as pain, irritation, itching, bleeding, or discoloration after leakage of injection into the skin. Venofer is for use in adults and children at least 2 years old. fever, cold or flu symptoms (sore throat, cough, stuffy nose, sneezing); bruising or irritation where the medicine was injected. Common and Rare Side Effects for Venofer Vial - WebMD (A class of medications describes a group of drugs that work in the same way.). Which tests can diagnose iron deficiency anemia? Injectafer may not be right for you if you have certain medical conditions or other factors affecting your health. Its important to note that youll get Injectafer doses from a doctor or healthcare professional in a medical facility. It can be given as a slow injection over 2 to 5 minutes or as an infusion. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Selected from data included with permission and copyrighted by First Databank, Inc. Do not flush down a toilet or pour down a drain unless you are told to do so. Version: 7.01. Venofer (iron sucrose injection, USP) is indicated for the treatment of iron deficiency anemia (IDA) in adult and pediatric (2 years of age and older) patients with chronic kidney disease (CKD), and is administered only by or under the supervision of your healthcare provider. Your doctor will do laboratory tests to monitor your response. If you are breastfeeding, tell your doctor if you notice diarrhea or constipation in the nursing baby. A very serious allergic reaction to this drug is unlikely, but get medical help right away if it occurs. Theyll recommend how to manage your condition. Potentialside effectsthat are usually mild may include, but are not limitedto: Theseside effectsmay not impact life too much and may only be temporary. If you notice any changes to your normal blood pressure, call your doctor right away. generalized weakness. Foods rich in iron include meats (especially liver), eggs, raisins, figs, broccoli, brussels sprouts, beans, lentils, and iron-fortified or enriched cereals. Check with your pharmacist. Procedure Details Injectafer is approved for use in adults who either: Injectafer contains the active drug ingredient ferric carboxymaltose. In this group, after 35 days of treatment: In clinical studies, Injectafer was effective in treating IDA in adults with CKD who didnt require dialysis. But its only approved for use in people with CKD who may or may not need dialysis. Throw away unused or expired drugs. treatment schedule in further detail. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. There are currently no generic forms of either drug. In this study, researchers compared Feraheme treatment with that of ferric carboxymaltose (the active drug in Injectafer). If you have questions about side effects, call your doctor. And theyll recommend how soon after starting the drug you need to have this level checked. The researchers found that compared with their hemoglobin level before the study: But the actual price youll pay for either drug depends on your insurance plan, your location, and the pharmacy you use. FG Trade/E+ sia Getty Images People in the study received treatment with either Injectafer or Venofer. The infusion will take between 15-30 minutes if it is given in. For more information about Injectafers approved uses, see the section Injectafer uses below. The Food and Drug Administration (FDA) approves prescription drugs such as Injectafer to treat certain conditions. This is a sudden response affecting the entire body, which sometimes happens to people who are allergic to peanuts or beestings. Venofer may cause significant hypotension (decreased blood pressure). Injectafer infusions are given over a period of at least 15 minutes. Side effects are uncomfortable reactions to medications or drugs. (IV iron is absorbed by the body more rapidly than oral iron.) When the toxins are released into the air, they can be inhaled and cause irritation to the lungs. Consult your pharmacist or local waste disposal company. Venofer may cause serious side effects including: problems with your dialysis vein access point, chest pain, severe headache, blurred vision, pounding in your neck or ears, lightheadedness, pain or swelling, bloating, nausea, vomiting, loss of appetite, diarrhea, and fever Get medical help right away, if you have any of the symptoms listed above. On the other hand, some people may have a poor appetite that goes away when their anemia is treated. Injectafer comes as a liquid solution inside vials. The way thatprescription drugsand evenover-the-countermedications interact with a body is influenced by manyfactors. pain in the arms or legs. How Long Do COVID Vaccine Side Effects Last? Doctors Explain - Bustle After receiving IV iron therapy, you will be monitored for 30 minutes to make sure you do not have an allergic reaction or a drop in blood pressure. Does Venofer Vial interact with other medications? If youre not sure if youll need to get prior authorization for Injectafer, contact your insurance company. Pain, swelling, or redness at the injection site may occur. The information provided is not intended to replace your healthcare provider's medical advice. administered at your doctors office or an infusion center. You may need extra iron because of blood loss during kidney dialysis. Any long-term side effects/dangers from iron infusions? Notify your healthcare provider of all medical conditions and any medications, including supplements you are taking. These lists contain up to 10 of the most common mild side effects that can occur with Injectafer, with Feraheme, or with both drugs (when taken individually). After 5 weeks of treatment: This study didnt determine if either drug was better than the other. * Feraheme has a boxed warning for this side effect. Best food forward: Are algae the future of sustainable nutrition? Tell your doctor if you are taking iron supplements or other iron-based oral medications. upper respiratory infection. Joint pain. To help make sure that you dont miss appointments for your Injectafer doses, try setting an appointment reminder on your phone. Some people may also experience skin irritation from the adhesive tape and other medical equipment used during the procedure. Reblozyl is a brand-name prescription medication used to treat anemia in certain blood disorders. What are the side effects of Venofer? If you have questions about the best diet for you during Injectafer treatment, talk with your doctor. chills difficulty with moving ear congestion or pain flushed, dry skin fruit-like breath odor increased hunger or thirst increased urination lack or loss of strength pain or redness at the injection site pale skin at the injection site runny nose, sneezing sore throat unexplained weight loss Rare Burning, dry, or itching eyes If you need to store Venofer at home, talk with your doctor, nurse, or pharmacist about how to store it. Drug class: Iron products. Erectile dysfunction, anothercommonside effect, can affect life significantly leading to depression and failedrelationships. Iron infusion: Uses, benefits, and what to expect - Medical News Today Venofer Side Effects. Many people using this medication do not have serious side effects. There isnt a known interaction between Injectafer and alcohol. Low blood pressure. Venofer - Iron sucrose uses, dose and side effects - zeepedia.com However, there has been a report of delayed allergic reaction in someone receiving a second dose of Injectafer. These lists contain examples of serious side effects that can occur with Injectafer, with Venofer, or with both drugs (when taken individually). However, be sure to take the dosage your doctor prescribes for you. Iron sucrose injection has a molecular weight of approximately 34,000 - 60,000 daltons and a proposed structural formula: <> Enter your medication into the WebMD interaction checker, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Fitness vs. But its important to note that these studies werent designed to show whether Injectafer is safe to use during pregnancy. However, many people have no side effects or only have minor side effects. However, side effects at the 150 mg dose may indicate that you might not . The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. The drug helps increase your hemoglobin level back to a value thats within the normal range. (A generic drug is an exact copy of the active drug in a brand-name medication.) Speak to yourhealth careprofessional for medical advice on if the dosage should bereduced. Also tell them about any vitamins, herbs, and supplements you use. Theseside effectscan range from being mild tosevere. Venofer is not for treating other forms of anemia not caused by iron deficiency. Some drugs may have another patient information leaflet. * Sex and gender exist on spectrums. Before taking Injectafer, be sure to tell your doctor or pharmacist about any medications you take, including any over-the-counter vitamins or supplements. They can tell you about other medications that may work well for you. Maximum concentrations of Injectafer are achieved within 15 minutes to 1.21 hours following administration. The recommended dosing guidelines of Injectafer for treating IDA are based on patient weight, as follows: Injectafer contains ferric carboxymaltose, which is a polymer that releases iron into the body. You should always consult your doctor or another healthcare professional before taking any medication. You should not receive Venofer if you have ever had an allergic reaction to an iron injection, or if you have iron overload (the buildup of excess iron) or hemochromatosis. Venofer and the Venofer logo are registered trademarks of Vifor (International) Inc., Switzerland. For instance, those who are taking other medications or supplements as part of home remedies may continue to suffer from the ill effects of their new medication because they dontinteract. What is Venofer? Venofer (iron sucrose): Anemia Medication Uses & Side Effects - MedicineNet However, not treating iron deficiency anemia during pregnancy may cause complications such as premature birth or low birth weight. Since side effects are similar between 150 mg and 300 mg, a larger dose may increase severity or frequency of side effects. Venofer Intravenous: Uses, Side Effects, Interactions, Pictures - WebMD Constipation,dry mouth, headaches, upset stomach, and many othercommonside effectscan greatly affect peoples quality of life, though. But for other people, their IDA returns after treatment with Injectafer. Your dosage and length of treatment are based on your medical condition, age, and response to treatment. Injectafer (ferric carboxymaltose): Side effects and more Iron is a vital mineral in the body, central to transporting oxygen around the body in the hemoglobin. Side effectsare uncomfortable reactions to medications or drugs. I was surprised too but the Dr said it definitely sounds like a reaction. taste impairment. These nutrients include iron, vitamin B12, and folate. Its possible to get rid of or reduce the severity ofside effects. In some cases, they may even recommend that you use a drug other than Injectafer to treat your anemia. Venofer (iron sucrose) Uses, Dosage, Side Effects, FAQ - MedicinesFAQ The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Common side effects of Venofer include: muscle cramps, nausea, vomiting, stomach pain, strange taste in the mouth or decreased sense of taste, diarrhea, constipation, headache, cough, sore throat, sinus pain, congestion, back pain, joint pain, dizziness, weakness, tired feeling, anxiety, ear pain, swelling of the arms/legs, or People who weigh less than 110 lb (about 50 kg) will receive two separate Injectafer doses of 15 mg/kg of body weight. The signs and symptoms of anaphylaxis include dizziness or fainting, skin flushing and itchiness, difficulty breathing, rapid heart rate, low blood pressure and sudden anxiety. Pain in your limbs. With IDA, you have anemia (low red blood cell level) thats due to not having enough iron in your body. This hormone is made by your kidneys. If youre taking iron pills, be sure to tell your doctor before starting Injectafer. As a result, you may not make as much EPO as usual. Call your healthcare provider or get medical help right away if you have symptoms of an allergic reaction, including but not limited to rash, chest pain, cough, dizziness, passing out, shortness of breath, sweating or throat tightness.